The door clicks shut behind Grace as distant moans thicken into a rhythm. A rusted case glares from the desk, its lock refusing to give. I felt that instant—your inventory light flashing, options thin.
I’ve played this section until the clues started to feel personal. I’ll walk you through the Lead Researcher’s Office puzzle in Resident Evil Requiem so you can get the code, the corrosive, and the item inside without wasting ammo or time.
Lead Researcher’s Office puzzle solution in Resident Evil Requiem
A framed photo on an office shelf often hides the detail you miss at first.
Two in-game photos — Lead Researcher’s Picture 1 and Lead Researcher’s Picture 2, found in the Chairman’s Office earlier — actually show the combination carved into the background of the device. Those two photos are a breadcrumb trail to the combination, so treat them like evidence, not decoration.
How do I solve the Lead Researcher’s Office puzzle?
Open the case only after you have the Corrosive from the Conference Room (more on that below). Once the lock is melted, set the sequence shown in the photos exactly as follows:
- Star
- Sun
- Moon
- Sun
Inside you’ll find another key item that moves Grace’s path forward. The solution is simple; missing the Corrosive is what stalls most players.

Where to find the Corrosive and what blocks you
Conference rooms often smell of stale coffee and stacks of forgotten memos.
The Corrosive you need sits in the Conference Room of Rhodes Hill. To reach it you’ll have to move past a massive Chunk encounter — a grotesque, obese enemy that dominates the area until you coax it out of the room or create a distraction. There are also several standard zombies, including a singer-type that’s alarmingly persistent at close range.
Where is the Corrosive in Rhodes Hill?
Clear or bypass Chunk, deal with the zombies, grab the Corrosive, then bring it back to the Lead Researcher’s Office. Use the Corrosive to melt the lock on the case shown in the photos and input the Star–Sun–Moon–Sun sequence.

Tactical notes, platform context, and one quick sanity check
A desk lamp often shows smudges where fingers trace the same spot again and again.
If you’re playing on PlayStation, Xbox, or Steam, this sequence and the item placements are consistent across versions released by Capcom. I recommend conserving shotgun shells and using doors and vertical space to thin groups — treat the fight with Chunk as a resource-management puzzle as much as a combat encounter. The clues are a rusted key in a junk drawer: small, easy to miss, but decisive when used.
One final sanity check: if the case won’t open after you apply Corrosive, double-check those two photos in the Chairman’s Office. Miss one tiny symbol and the device won’t yield.
You’ve got the code and the route; will you take the risk to sprint for the next door or methodically clear the record room and guarantee your progress?