I touched down on the Endgame arena and a wave of Chitauri swept past my feet. For a full hour I watched teammates get crushed and respawn, then found a rhythm that actually worked. By the third run I knew which heroes made Thanos feel manageable and which made the fight a chore.
Every evening my Discord blows up with one question: which heroes cut through Thanos fastest? Below I tested every roster entry across phases, and these ten stood out on repeat runs.
I’m writing this as someone who chased percentages on YouTube clips, scanned Reddit threads, and played rounds on iOS and Android. You don’t need to grind endless matches to be useful — you need the right pick and a short plan. The arena becomes a pressure cooker; if you know how to vent it, you win faster.
Human Torch
If you want to riddle Thanos’ health bar without babysitting minions, pick the Human Torch. Staying airborne removes most of the ground clutter and lets you stack constant Fire Clusters. Start fights by boxing Thanos with Blazing Blast to keep him inside your damage field, then spam Fire Clusters and finish with Supernova when the health bar dips.
Jubilee
Jubilee is my go-to when the team needs steady DPS plus on-demand healing. Season 10.5 buffs made Blooming Balls and Fireworks Finale far more reliable in later phases. Drop Blooming Balls near teammates, inflate them, and watch health stick — save Fireworks Finale for the second phase when the arena fills with Chitauri and Thanos starts using stone-driven attacks.
Storm
Storm turned my theorycraft into results. Her aerial Wind Blades and Omega Hurricane clear minions while keeping pressure on Thanos’ hitbox. She’s less slippery than some flyers, so you must respect Thanos’ telegraphed heavy attacks — position at mid-distance and use Wind Blades to kite the big swings.
Phoenix
Phoenix is pure distance control. You can stand near the arena edge and punish Thanos’ wide swings with sustained Cosmic Flames. Use Telepathic Illusion and Dark Ascent to reposition when the Infinity Stones flash up — timing Endsong Inferna centrally will shred minions and send Thanos’ health dropping fast.
Iron Man
Iron Man still plays the role he did in theaters: damage, distance, and clutch finishers. Use Armor Overdrive to stack repulsor damage, and his new auto-tracking missiles from Season 10.5 lock to minions and Thanos alike. Hold Invincible Pulse Cannon until Thanos repositions, then fire to punish predictable movement.
Moon Knight
Moon Knight turns the swarm into his advantage. Crescent Darts bounce across clustered minions, and Ankhs let you pressure Thanos while chipping the army away. Because survivability is lower without elevation, pair Moon Knight with a healer or play cautiously around group heals.
Scarlet Witch
Wanda remains surgical against both minions and Thanos. Chaos Control and Scarlet Hex chew through squads while Sorcerer Supreme tools let you harvest Thanos’ life. If you can time Mystic Projection to dodge heavy counters, you’ll survive much longer and keep the pressure steady.
The Hood
If your team needs a Vanguard that still deals ranged damage, The Hood is the pick. Build Demonic Energy with pistol fire, hit Half-Demon for movement and damage, and save Demon of the End for phases when Thanos shows predictable behavior. His aim is easier against Thanos’ large model.
Ultron
Ultron doubles as a strategist and aerial damage dealer. His drone play keeps allies topped while he keeps Encephalo-Ray on Thanos. Use Rage of Ultron during heavy ship strikes or stone-powered sequences to sustain teammates and push through the damage spike.
Jeff the Land Shark
Jeff is the quiet MVP for sustain-heavy teams. Joyful Splash heals at range and damages minions, Hide and Seek buys you escapes, and Healing Bubbles keep the team alive in congested fights. You can’t swallow Thanos with It’s Jeff, but the healing zone often keeps allies in the fight longer than expected.
How do I beat Thanos in Avengers Endgame PvE mode?
Short answer: focus damage on Thanos’ headbox and avoid getting boxed by minions. Pick an aerial or range hero to ignore ground clutter, save movement abilities for stone-driven bursts, and coordinate one large finisher when Thanos is static. Tools like Discord and Reddit clips helped me time those finishers; YouTube guided my timing on phase changes.
Which hero should I pick if my squad needs a healer?
Jubilee and Ultron are the best two choices. Jubilee’s Blooming Balls offer constant, portable heals, while Ultron’s drones provide automated triage and damage at altitude. If you’re solo-queue and want low-friction healing, Jeff the Land Shark is the simplest to play: place healing zones and stay safe.
A final tip from my runs: treat Thanos’ phases like timing windows rather than damage sponges. Manage one heavy burst per window, rotate cooldowns, and don’t crowd him when the ships show up. Human Torch or Iron Man will punish poor spacing; Moon Knight and Scarlet Witch will clean up the leftovers.
I’ve run these picks across iOS and Android builds, watched NetEase Games patch notes, and chased community builds on Discord. Phoenix can feel like a flare gun in a blackout — brief, bright, and game-changing when it hits. Which hero surprised you on your runs and why?