Meet Vex, the designated Siren in Borderlands 4, who shines as arguably the most versatile witch in the franchise’s history. Although she channels the same supernatural phase energy as her Siren peers, Vex feels more akin to Fl4K, the Beastmaster from Borderlands 3. With her ability to summon minions and empower herself for battle, she offers unique playstyles. Whether you’re eager to delve into cooperative gameplay or crave a solo adventure, this guide will help you build the optimal Vex setup for maximum impact.
With years of gaming expertise under our belt, we understand the intricacies of character builds in Borderlands. By focusing on an ideal combination of skills and gear, we want to make sure you dominate the battlefield every time you log in.
The Ultimate Vex Build in Borderlands 4

- Primary Skill Tree: Vexcalation
- Action Skill: Incarnate
- Damage Type: Kinetic
This Vex build is designed for max-level characters, enabling you to explore powerful Augments and Action Skills. Our focus is heavily on Kill Skills, which provide a continuous boost to Vex, though it does forgo summoning. The primary damage type of choice is Kinetic, enhanced by a bleed effect. Expect to equip Jakobs pistols and shotguns for maximum effectiveness as you rain down chaos in enemy camps.
The Incarnate Action Skill is central to this setup, allowing Vex to restore her health while dealing damage to foes. The phase explosion orb also gives you the option to damage enemies while increasing your movement speed. Aim to keep Incarnate active, especially with the Full Moon skill that enhances action skill cooldown rates as long as your shields are intact.
As for skill choices, we recommend focusing on Kinetic damage boosters, including Bloodletter, Material Components, and Leeching Attunement for that added lifesteal advantage. Drink Full can significantly ramp up your fire rate, stacking up to 50. Don’t overlook Mortal Terror; this will allow you to trigger Kill Skills with critical hits on enemies, maximizing your offensive capability.
Here’s how you should allocate your skill points for optimal performance:
Skill Name | Points | Description |
---|---|---|
Incarnate (Action Skill) | – | Vex creates a phase explosion, dealing damage to nearby enemies and fully restoring her health. While active, Vex can cast Eldritch Blast and gain increased movement speed. Hold the action skill button to end Incarnate early for a partial cooldown refund. |
Guns and Needles | 3/3 | Kill Skill: Restore Repkit Cooldown by a Percentage |
Leeching Attunement | 5/5 | Attune Skill: While Vex is attuned to kinetic, she gains increased lifesteal and reload speed, lasting for a while after switching attunement. |
Bloodletter | 5/5 | Gun and skill critical hits can apply bleed, causing kinetic damage over time. Bleed is influenced by status effect application chance. |
Geistwave | – | Augment: Launch a Geistwave instead of a Phase Explosion, dealing Ordinance damage and increasing damage on affected enemies for a short duration. |
Energy Vampire | – | Augment: Inflict damage over time to nearby enemies and gain overshield for each affected target. |
Material Components | 5/5 | Passive: Boosts kinetic damage and kinetic status effect damage. |
Conjunction | 5/5 | Passive: Increases gun damage based on shield status and offers damage reduction as health decreases. |
Iron Maiden | – | Augment: Restores shield for each enemy hit by Phase Explosion and Eldritch Blast while boosting their damage based on Vex’s current shield. |
Witchy Trigger Finger | – | Augment: Damaging enemies with Eldritch Blast or Phase Explosion reloads Vex’s weapon and grants damage boosts for a limited time. |
Grave Vitality | – | Kill Skill: Increases maximum health and health regeneration. |
Grave Harvest | – | Augment: Killing an enemy while Incarnate is active creates a Soul Orb that deals status effect damage over time. |
Essence Leech | 5/5 | Grants lifesteal, with the effect doubled when an Action Skill is active. |
Mortal Terror | 5/5 | Chance to trigger Kill Skills upon critical hits. |
Full Moon | 5/5 | Passive: Enhances Action Skill and Ordinance cooldown rate depending on shield status. |
A Deeper Grave | 3/3 | Passive: Extends the duration of Vex’s Kill Skills. |
Blood is Power | 3/3 | Passive: Increases Kinetic Damage with Guns based on Lifesteal when health is full. |
Ars Arcana | 5/5 | Boosts Vex’s skill damage significantly. |
Keep an eye out for class mods that enhance skills in the Vexcalation tree, especially focusing on Grave Harvest, Iron Maiden, and Energy Vampire.
That’s a wrap on the best Vex build in Borderlands 4. We can’t wait to hear how this build changes your gameplay experience. Share your thoughts and successes in the comments below!