Marathon Protect/Destroy 1: How to Destroy the Biosample Analyzer

Marathon Protect/Destroy 1: How to Destroy the Biosample Analyzer

I nearly blew a perfect Dire Marsh run the first time I chased Protect/Destroy 1. You sprint into Quarantine with a scanner pinging and the run feels like a lit fuse. If you keep your head, I’ll show you the exact route that closes this contract in one clean loop.

I’ve run this path enough to count the predictable choke points. You’ll move faster if you follow the order: destroy, grab, deliver.

Marathon Protect/Destroy 1 contract walkthrough

Observation: Quarantine sits on the map’s western edge, a squat building crowded with pods and supply containers.

The Protect/Destroy 1 task is split into three clear objectives that must be finished on the same run. Treat this as a single sequence — interrupting the flow costs time and increases risk. Here’s the breakdown so you don’t waste a spawn.

  • Destroy the biosample analyzer inside west Quarantine
  • Acquire the UESC Biohazard Sample
  • Deliver the sample to DCON

How do I destroy the biosample analyzer in Marathon?

Start a fresh round on Dire Marsh and head straight west for the Quarantine POI. Don’t detour for loot — enemies respawn and timers are short.

Enter the main building, clear the immediate UESC patrols, and sweep the pod room. You’ll see a stairwell painted yellow above a set of containers — take those up. The quest marker will switch to the analyzer’s position once you’re on the second floor.

Quarantine POI in Marathon
Screenshot and remix by Moyens I/O
The Yellow stairs that leads to the bio-sample analyzer
Image via Bungie

Once you find the biosample analyzer on the second floor, you don’t need a special tool — a few shots will destroy it and drop the UESC Biohazard Sample. Keep movement tight: other players or AIs will rush the area once the alarm triggers.

bio-sample analyzer in Quarantine
Image via Bungie

How do I deliver the UESC Biohazard Sample to DCON?

DCON terminals are scattered across Dire Marsh; one sits right beside the Quarantine building. If you clear the POI quickly, you can hand the sample over there and finish the contract without leaving the area.

DCON locations in Dire Marsh
Screenshot and remix by Moyens I/O

Approach the DCON, add the UESC Biohazard Sample into its inventory, and wait a few seconds for the transfer. The DCON will acknowledge and the Protect/Destroy 1 contract completes. If the nearest DCON is contested, sprint to the next marker rather than fighting — time is the enemy.

Quick tips that shave time and stress

Observation: Players who sprint without a plan usually trade a clean completion for a messy scramble.

  • Run solo if you can — fewer unpredictable teammates means fewer delays.
  • Bring a short-range weapon for the room clear and a fast DPS option to drop the analyzer quickly.
  • If you’re streaming or posting, credit Bungie screenshots sparingly and tag Moyens I/O where you remix images.

Treat the path like a mapped route: move with purpose, hit the analyzer, grab the sample, then feed the DCON — smooth and direct, like a map with an X. Ready to test whether you can close this contract clean the next time you queue?