Updated on June 26, 2025: Adjusted the tier list and Reroll guide for post-release.
When diving into Marvel Mystic Mayhem, you face the exciting challenge of picking the perfect heroes for your team. This game boasts an impressive roster, but with a limited team size, it’s vital to understand the strengths of each hero. I’ll break down hero rankings, provide tips, highlight best Artifacts, and detail synergies. To wrap things up, I’ll also include a Reroll guide since starting with a strong hero can significantly impact your early game performance. Here’s my Marvel Mystic Mayhem tier list and Reroll guide.
Marvel Mystic Mayhem Hero Tier List
In Marvel Mystic Mayhem, the strongest heroes typically shine within their respective roles. For Defenders, select characters with high tank capabilities and taunts. For Strikers and Fighters, prioritize high damage and agility. Controllers should excel in healing or possess great utility and crowd control. Below, I’ll analyze each hero along with tier breakdowns:
- S-Tier: Top choices in every class recognized for outstanding damage, tanking, healing, and utility.
- A-Tier: Strong alternatives to S-Tier heroes that still deliver substantial power.
- B-Tier: Heroes that shine in certain builds or face challenges fitting into broader teams.
- C-Tier: Limited flexibility, excelling only in specific scenarios, but overall less powerful.
Now, let’s analyze the top-tier heroes based on their ranks and provide valuable tips.
S-Tier Heroes
| Hero | Ranking Reason | Tips |
|---|---|---|
 Juggernaut – Defender – Mystic Arts – Legendary |
Unmatched tanking abilities; needs leveling for Taunt to maximize potential. | Best Artifacts: Force Field Glove, Sling Ring. Highlights: Blessing of Vishanti, Monster Within. |
 Doctor Strange – Controller – Mystic Arts – Legendary |
Highly adaptable with substantial healing and utility capabilities. | Best Artifacts: Gamma Mutagen, Force Field Glove. Highlights: Vow to Protect, Ancient Frontier. |
 Thor – Fighter – Energy – Legendary |
Excels in damage output and mobility; versatile among Fighters. | Best Artifacts: S.H.I.E.L.D Flight Pack, Hand’s Shuriken. Highlights: The Worthy Ones, Ambition. |
 Iron Man – Striker – Energy – Legendary |
Top choice for AOE damage; requires defensive items due to limited defenses. | Best Artifacts: Hand’s Shuriken, Midnight Gun. Highlights: Fight as One, Great Minds. |
 Scarlet Witch – Striker – Mystic Arts – Legendary |
Ideal for clearing enemies; her Ultimate is highly effective against bosses. | Best Artifacts: Hand’s Shuriken, Midnight Gun. Highlights: Fight as One, Great Minds. |
 Emma Frost – Controller – Mutation – Legendary |
Versatile healer and off-DPS with a powerful debuff ability. | Best Artifacts: Avengers ID Card, Gamma Mutagen. Highlights: Ancient Frontier, Weavers of Dream. |
 Armor – Defender – Mutation – Epic |
Offers a strong blend of damage and tank capabilities with stunning abilities. | Best Artifacts: Asgard Shield, Gamma Mutagen. Highlights: Light in Darkness, Learn from the Best. |
A-Tier Heroes
| Hero | Ranking Reason | Tips |
|---|---|---|
 Hulk – Defender – Energy – Epic |
Offers great defenses and buffs but lacks a Taunt. | Best Artifacts: Force Field Glove, Sling Ring. Highlights: Blessing of Vishanti, Stand Strong. |
 Lady Bullseye – Striker – Weaponry – Epic |
Features high chain damage potential with manageable cooldowns. | Best Artifacts: Hand’s Shuriken, Unstable Molecules. Highlights: Fight as One, A Hired Blade. |
 Psylocke – Fighter – Mutation – Epic |
Combines single and AOE damage effectively with high mobility. | Best Artifacts: Hand’s Shuriken, Unstable Molecules. Highlights: The Worthy Ones, Rising from Ashes. |
 Sentry – Defender – Cosmic – Epic |
Provides a good tank alternative with utility. | Best Artifacts: Force Field Glove, Sling Ring. Highlights: Blessing of Vishanti, Stand Strong. |
 Sleepwalker – Controller – Energy – Epic |
Offers decent DPS with a powerful Ultimate. | Best Artifacts: Force Field Glove, Avengers ID Card. Highlights: Vow to Protect, Guardian of Reality. |
 Misty Knight – Striker – Weaponry – Epic |
High damage potential; requires good positioning. | Best Artifacts: Hand’s Shuriken, Unstable Molecules. Highlights: Fight as One, Raise Like the Phoenix. |
B-Tier Heroes
| Hero | Ranking Reason | Tips |
|---|---|---|
 Moon Knight – Fighter – Concussive – Epic |
Struggles with versatility but a flexible team member. | Best Artifacts: Avengers ID Card, Gamma Mutagen. Highlights: The Worthy Ones, Touched by Khonshu. |
 Spider-Man – Controller – Concussive – Legendary |
Lacks healing but excels in crowd control and debuffs. | Best Artifacts: Hand’s Shuriken, Unstable Molecules. Highlights: Fight as One, Great Minds. |
 Angela – Defender – Weaponry – Epic |
Offers decent damage, but a lack of Taunt holds her back. | Best Artifacts: Asgard Shield, Gamma Mutagen. Highlights: Blessing of Vishanti, Learn from the Best. |
 Black Knight – Fighter – Mystic Arts – Epic |
Possesses strong potential with specific hero pairings. | Best Artifacts: S.H.I.E.L.D Flight Pack, Hand’s Shuriken. Highlights: The Worthy Ones, Hear Me Roar. |
 Moon Girl – Controller – Weaponry – Legendary |
Great DPS but lacks utility to compete with top Controllers. | Best Artifacts: Avengers ID Card, Gamma Mutagen. Highlights: Ancient Frontier, No Strings on Me. |
 Doppleganger – Fighter – Cosmic – Epic |
Good mobility, shines with fast attacks and specific synergies. | Best Artifacts: S.H.I.E.L.D Flight Pack, Hand’s Shuriken. Highlights: The Worthy Ones, By Cyttorak’s Command. |
 Echo – Fighter – Weaponry – Epic |
Best with high damage heroes for optimal synergy. | Best Artifacts: Hand’s Shuriken, Midnight Gun. Highlights: War Paint, Ambition. |
 Storm – Striker – Mutation – Legendary |
Lower DPS than others in the Legendary tier but useful for debuffs. | Best Artifacts: Hand’s Shuriken, Unstable Molecules. Highlights: Fight as One, Friends on Street. |
C-Tier Heroes
| Hero | Ranking Reason | Tips |
|---|---|---|
 Falcon – Controller – Concussive – Epic |
Great mobility but lacks in sustained DPS and utility. | Best Artifacts: Avengers ID Card, Hand’s Shuriken. Highlights: Ancient Frontier, No Strings on Me. |
 Thread – Striker – Mystic Arts – Epic |
Useful in summoning team compositions but limited otherwise. | Best Artifacts: Gamma Mutagen, Avengers ID Card. Highlights: Fight as One, Ancient Allies. |
 Dreamqueen – Controller – Mystic Arts – Epic |
Strong DPS potential, but lacks CC and healing. | Best Artifacts: Avengers ID Card, Gamma Mutagen. Highlights: Ancient Frontier, Guardian of Reality. |
 Mister Negative – Fighter – Mystic Arts – Epic |
Requires specific synergy for effectiveness, otherwise underwhelming. | Best Artifacts: Gamma Mutagen, Hand’s Shuriken. Highlights: The Worthy Ones, Rising from Ashes. |
 Man-Thing – Controller – Mutation – Epic |
Shines in summon comp; offers low base performance otherwise. | Best Artifacts: Force Field Glove, Avengers ID Card. Highlights: Guardian of Reality, Vow to Protect. |
Marvel Mystic Mayhem Reroll Guide
To get the most from Marvel Mystic Mayhem, consider these important points about the Reroll system:
- Gacha Unlocks at Level 10: Reach Level 10 to access Gacha Banners and the essential resources to make calls. This typically takes around 15 to 20 minutes through Story and Daily missions. Remember to disable ultimate animations via Three Vertical Lines (Top Right) > Settings > Battle Tab > Do Not Play Ultimate Move Full Animation for quick rerolls.
- Banners to Spin On & Which Heroes to Get: Following enough spins from your resources, avoid the Iron Man Forge the Future banner and aim for others with higher chances of obtaining powerful heroes like Juggernaut, Doctor Strange, Thor, and Scarlet Witch. Using the Path to Legends can secure a guaranteed S-Tier character after 40 calls, making it worthwhile to reroll.
- How to Reroll: If your initial roll isn’t what you hoped for, you can reroll your account by following these steps:
- Tap the three vertical lines in the top right.
- Go to Settings.
- Tap User in the lower left.
- Access the last tab on the left.
- Tap Continue on Start a new game.
That’s it for my detailed Marvel Mystic Mayhem tier list and reroll guide. Don’t forget to explore related content for more tips and free goodies available through in-game codes. For additional resources, check out Moyens I/O.