The boss’s health bar was a sliver, but my damage was flatlining. All my Plant Brainrot Simulator experiments, all the fruit wasted… gone. Then, I swapped one mutation and watched the numbers explode, and the boss melted like butter. Here’s how you can avoid my mistakes with a Plant Brainrot Simulator Mutations tier list designed to maximize your plant power.
Plant Brainrot Simulator: Best Mutations
Ever notice how one bad apple spoils the bunch? In Plant Brainrot Simulator, one bad mutation can ruin your entire strategy. The game prevents stacking, so choosing the right mutation is paramount. Currently, Darkness is king for bosses and World Boss events, while Bomb dominates wave clear and progression. I suggest merging plants for weight first, as wasting fruit on weak plants is a rookie error. Merging combines two of the same plant, up to 5 stars, increasing weight to 201kg (more weight = more damage). Position Bomb on your highest DPS plant and support it with Darkness.
- Plants can sometimes spawn with random mutations
- Spam KG Fruit on the plant you want to place Bomb or Darkness on for more weight
- More weight = more damage
How do you get mutations in Plant Brainrot Simulator?
Mutations happen randomly. Sometimes you’ll get lucky, and a plant will spawn with a mutation. If not, keep using KG Fruit on your plants; you will increase your chances this way. Remember, focusing on your best plant for the mutation that suits it will optimize your gameplay.
S-Tier Mutations
Think of “S-Tier” mutations as your team’s star players, those that consistently deliver when it matters. Their impact can shift the entire dynamic of a battle.
| S-Tier Mutation | Effect | Why S-Tier |
|---|---|---|
 Darkness Mutation |
Attacks can knock enemies back | • Currently, the highest damage multiplier along with the crowd control effect • The best mutation for clearing bosses and World Bosses • I recommend splitting your plants into just Darkness and Bomb plants |
 Bomb Mutation |
Attacks become area-of-effect dealing damage to multiple enemies around the target | • The best DPS for clearing waves due to massive AOE damage • The best mutation for progression |
A-Tier Mutations
A-Tier mutations are like dependable utility players. They might not steal the show, but they will deliver results when integrated into a team. Their consistent performance makes them valuable assets.
| A-Tier Mutation | Effect | Why S-Tier |
|---|---|---|
 Venom Mutation |
Attacks can slow enemies | • The best stalling effect after Darkness• That said it’s lower DPS |
 Frozen Mutation |
Attacks can freeze enemies for a short duration | • Less reliable CC effect than Venom but still good in a pinch• CC effects are in general more important than better single-target DPS which is why Frozen is better than Flame |
What is the best strategy for Plant Brainrot Simulator Mutations?
The best mutation strategy is less about chasing individual mutations and more about plant weight and understanding team synergy. Consider weight a multiplier for damage and your mutations as force multipliers. The plant is the engine, and the mutations are the fuel.
B-Tier Mutations
B-Tier mutations are a mixed bag, useful in specific circumstances but generally outclassed. They’re the kind of player you might sub in during a pinch, but you wouldn’t build your strategy around them.
| B-Tier Mutation | Effect | Why S-Tier |
|---|---|---|
 Flame Mutation |
Attacks can burn enemies and deal extra damage | • Great for beginners• That said, CC/Stalling effects like knockbacks and slows are better than single-target damage• Bomb outscales Flame for DPS• That said Flame is slightly better against single targets like bosses and worldbosses though Darkness beats it there |
That’s all for my mutation tier list. Don’t forget the Plant Brainrot Simulator codes for freebies! Is the “perfect” mutation setup really the key, or is it just min-maxing gone too far?