I hit the Apollo Disruption rotation and watched the Axi relic drop like a key on a crowded keyring. My squad sighed, someone swore, and I realized this was going to be one of those grinds you either love or hate. You can spend money and skip the squeeze — or play the long game and craft Afentis Prime piece by piece.
I’m a long-time Warframe player and writer; you’ve probably seen my posts on the Warframe Wiki or the forums. I’ll walk you through every relic you need, the best mission picks, and the smart ways to trade or farm so you don’t waste time or credits.
All Afentis Prime Relics in Warframe
I once queued a fissure with a full squad and watched three relics open in under ten minutes — that’s the practical reality of efficient farming.
Afentis Prime is part of the Jade Shadows: Constellations update and arrives with Styanax Prime. If you prefer a shortcut, there’s Prime Access for immediate access to the weapon — typically priced around $99 USD (€92). If you don’t want to spend that, the relic route is free but grind-heavy.
- Blueprint: Rare Axi A22
- Blade: Rare Meso A12
- Barrel: Uncommon Neo C8
- Handle: Common Lith Q3
Two Rare relics means patience or luck. I’ll give you maps, rotations, and the community tricks that tilt the odds in your favor. Use Warframe Market or the Trading chat if you want to skip the farming — many players trade intact relics and parts there.

What relics drop Afentis Prime?
The blueprint comes from Axi A22 (Rare). The other parts are split across Meso A12 (Blade, Rare), Neo C8 (Barrel, Uncommon), and Lith Q3 (Handle, Common). Aim for Axi and Meso runs first — they’re the slowest gates.
Where should I farm each relic?
Short, actionable options I use:
- Axi A22: Apollo Disruption on Lua. The B and C rotations guarantee an Axi relic — bring a fast, damage-light frame to clear quickly.
- Meso A12: Ukko node in the Void or the Disruption mission on Olympus (Mars). Both are solid for Meso drops.
- Neo C8: Ur node on Uranus — the disruption mission has B/C rotations with guaranteed Neo drops.
- Lith Q3: Hepit on the Void is absurdly quick with a speed build and gives a near-100% Lith relic chance.
How do Void Fissures and relic openings work?
Relic openings require Reactant. Each Void Fissure run awards Reactant when you kill Relic enemies; you need 10 Reactant total to open a relic. That means multiple fissure runs if you’re solo — or one clean run with a coordinated squad. The grind shifts from guessing to precision once you matchmake with players running the same relic.
My practical checklist:
- Set your squad’s mission filter in the mission browser to the relic type you want.
- Prefer Disruption nodes for repeatable, fast rotations.
- If you’re trading: check Warframe Market or the in-game trading channels for intact relics — some players sell Rare relics for platinum.
- Follow Digital Extremes’ patch notes and the Warframe subreddit for rotation updates and drop-fix alerts.
If you want to avoid farming entirely, consider the Styanax Weapons Prime Access packs on Steam or the official Warframe store, or buy the parts directly on Warframe Market. But if you’re farming, aim to stack fissures and open them in groups — the grind becomes a heat-seeking arrow once you join the right squad.
I’ve seen clans organize minute-by-minute farming sessions that net relics far faster than solo runs; you can mirror that approach or split time between trading and runs. Which route will you pick: paid Prime Access or a brittle, satisfying grind that tests patience and luck?